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AUTEURS ››Bouzid D, Bert J, Benhalouche S, Pradier O, Visvikis D, Boussion N
Titre ››Monte Carlo simulation on GATE V6.1 of an intraoperative device Intrabeam™ for early breast cancers.
DANS ››6th Intrabeam User's meeting
PUBLIE EN ››2012
TYPE PUBLI ››Conférence
LANGUE ››GB
Mots clés ››IORT, dosimetry, monte carlo, GATE
RESUME ››Introduction
This work is in the context of the Monte Carlo simulation with intraoperative radiotherapy. It aims to study the modeling of a new device installed at the University Hospital of Brest in 2011 named Intrabeam ™ on the platform GATE version 6.1.
Materials and Methods
The system Intrabeam™ is mainly dedicated for the treatment of breast cancer delivered to tumors smaller than 2 cm of diameter. Spherical applicators of varying diameters depending on the tumor size (3cm to 5cm), are mounted on the system to have an isotropic distribution of the dose. After extraction of the tumor by surgery, the system delivers a single dose fraction of 20 Gy to the surface of the applicator for irradiating the tumor bed through an X-ray beam of low energy (50 kV). This study includes two steps: (1) Modeling the Intrabeam™ device on the platform GATE version 6.1, (2) Preliminary dosimetric study on water phantom to locate the reliability and realism of the simulation.
Monte Carlo simulations on the GATE platform are precisely realized respecting the experimental geometry. The dose depth curves in water with the naked probe and the different applicator available are analyzed. The experimental dose measurements were performed with an ionization chamber PTW. The isotropy of the source was also checked. The simulation outcomes are compared with experimental measurements.
Results
The user interface of the platform GATE facilitates the Intrabeam system modeling. The simulation results obtained from the model created shows a good fit with the experimental measurements.
Conclusion
The Monte Carlo simulation allows a precise evaluation of the dose actually delivered and opened the way for personalized dosimetry taking into account the tissue inhomogeneities.

INSERM :
Bouzid D, Bert J, Benhalouche S, Pradier O, Visvikis D, Boussion N:Monte Carlo simulation on GATE V6.1 of an intraoperative device Intrabeam™ for early breast cancers... 6th Intrabeam User's meeting , 2012,,0-0,C,A,GB.]


BibTex :
@inproceedings{LaTIM-1748
author = {Bouzid D AND Bert J AND Benhalouche S AND Pradier O AND Visvikis D AND Boussion N}
title = {Monte Carlo simulation on GATE V6.1 of an intraoperative device Intrabeam™ for early breast cancers.}
booktitle = {6th Intrabeam User's meeting }
year = {2012}
}

Mise à jour le Mercredi, 04 Février 2009 12:36